IL-6 Protein, Sus scrofa (Pig), Recombinant

IL-6 Protein, Sus scrofa (Pig), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.2 kDa and the accession number is A4D862.

Pack Size	Availability	Price/USD	Quantity
20 μg	5 days	$ 357.00
100 μg	5 days	$ 695.00

Pack Size

Availability

Price/USD

Quantity

20 μg

5 days

$ 357.00

100 μg

5 days

$ 695.00

Description

IL-6 Protein, Sus scrofa (Pig), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.2 kDa and the accession number is A4D862.

Species	Sus scrofa (Pig)
Expression System	E. coli
Tag	Tag Free
Accession Number	A4D862
Synonyms	interleukin 6
Construction	The sus scrofa IL6 (NP_999564.1) (Pro29-Met212) was expressed with an initial Met.
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	21.2 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy