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Anti-GDF-6 Polyclonal Antibody
😃Good
Catalog No. TMAB-00758
Anti-GDF-6 Polyclonal Antibody is a Rabbit antibody targeting GDF-6. Anti-GDF-6 Polyclonal Antibody can be used in WB.
Anti-GDF-6 Polyclonal Antibody
Anti-GDF-6 Polyclonal Antibody
😃Good
Catalog No. TMAB-00758
Anti-GDF-6 Polyclonal Antibody is a Rabbit antibody targeting GDF-6. Anti-GDF-6 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Polyclonal Application: WB Reactivity: Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit) |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit) |
| Verified Activity | Sample: U251 (Human) Cell Lysate at 30 μg Primary: Anti-GDF6 (TMAB-00758) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 48 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Growth/differentiation factors (GDFs) are members of the TGF superfamily (1,2). Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1). GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3). Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members. GDF-3 is detectable in bone marrow, spleen, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4). GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. (5). GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs (6). GDF-6 and GDF-7 are closely related to GDF-5 (6). GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1). |
| Immunogen | KLH conjugated synthetic peptide: human GDF6 |
| Antigen Species | Human |
| Gene ID | 392255 |
| Uniprot ID | |
| Biology Area | Neurogenesis,Visual system,TGF |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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