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Anti-DUOX2 Polyclonal Antibody
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Catalog No. TMAB-00575
Alias Thyroid oxidase 2, THOX2, P138 TOX, p138 thyroid oxidase, NOXEF2, NADPH thyroid oxidase 2, NADPH oxidase/peroxidase DUOX2, NADH/NADPH thyroid oxidase p138-tox, Long NOX 2, LNOX2, Large NOX 2, Dual oxidase2, Dual oxidase 2
Anti-DUOX2 Polyclonal Antibody is a Rabbit antibody targeting DUOX2. Anti-DUOX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Anti-DUOX2 Polyclonal Antibody
Anti-DUOX2 Polyclonal Antibody
😃Good
Catalog No. TMAB-00575Alias Thyroid oxidase 2, THOX2, P138 TOX, p138 thyroid oxidase, NOXEF2, NADPH thyroid oxidase 2, NADPH oxidase/peroxidase DUOX2, NADH/NADPH thyroid oxidase p138-tox, Long NOX 2, LNOX2, Large NOX 2, Dual oxidase2, Dual oxidase 2
Anti-DUOX2 Polyclonal Antibody is a Rabbit antibody targeting DUOX2. Anti-DUOX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DUOX2 Polyclonal Antibody is a Rabbit antibody targeting DUOX2. Anti-DUOX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
| Alias | Thyroid oxidase 2, THOX2, P138 TOX, p138 thyroid oxidase, NOXEF2, NADPH thyroid oxidase 2, NADPH oxidase/peroxidase DUOX2, NADH/NADPH thyroid oxidase p138-tox, Long NOX 2, LNOX2, Large NOX 2, Dual oxidase2, Dual oxidase 2 |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Dog) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Apical cell membrane. Localizes to the apical membrane of epithelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Dual oxidase 2 (DUOX2), also designated NADPH thyroid oxidase 2, p138 thyroid oxidase or large NOX2, localizes to the apical membrane of epithelial cells. DUOX1, also designated NADPH thyroid oxidase or large NOX1, and DUOX2 are multi-pass membrane proteins predominantly expressed in thyrocytes, tracheal surface epithelial cells as well as thyroid, colon, duodenum, trachea and bronchium. DUOX1 and DUOX2 generate hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. In mucosa, DUOX proteins are involved in thyroid hormone biosynthesis and lactoperoxidase-mediated antimicrobial defense. Defects in the gene encoding for DUOX2 cause congenital hypothyroidism (CH), a disorder characterized by a defect in hydrogen peroxide production in the thyroid gland. |
| Immunogen | KLH conjugated synthetic peptide: human DUOX2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Thyroid axis |
| Molecular Weight | Theoretical: 173 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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