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Anti-MAP1D Antibody (8D880)
😃Good
Catalog No. TMAY-01282
Alias methionyl aminopeptidase type 1D (mitochondrial), Metap1l, MetAP 1D, MAP1D, MAP 1D
Anti-MAP1D Antibody (8D880) is a Mouse antibody targeting MAP1D. Anti-MAP1D Antibody (8D880) can be used in ELISA.
Anti-MAP1D Antibody (8D880)
Anti-MAP1D Antibody (8D880)
😃Good
Catalog No. TMAY-01282Alias methionyl aminopeptidase type 1D (mitochondrial), Metap1l, MetAP 1D, MAP1D, MAP 1D
Anti-MAP1D Antibody (8D880) is a Mouse antibody targeting MAP1D. Anti-MAP1D Antibody (8D880) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-MAP1D Antibody (8D880) is a Mouse antibody targeting MAP1D. Anti-MAP1D Antibody (8D880) can be used in ELISA. |
| Alias | methionyl aminopeptidase type 1D (mitochondrial), Metap1l, MetAP 1D, MAP1D, MAP 1D |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8D880 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MAP1D (rh MAP1D; TMPY-01344; NP_954697.1; Arg 44-Ala 335). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. The enzymes that catalyze this reaction are called Methionine aminopeptidases (MAPs). MAP1D is overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Downregulation of MAP1D expression by shRNA in HCT-116 colon carcinoma cells reduces anchorage-independent growth in soft agar. MAP1D binds two cobalt ions per subunit. The true nature of the physiological cofactor is under debate. MAP1D is also active with zinc, manganese, or divalent ions. MAP1D removes the amino-terminal methionine from nascent proteins. It may also play an important role in colon tumorigenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human MAP1D protein (TMPY-01344) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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