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Synonyms: Tyrosine-Protein Phosphatase Non-Receptor Type 6, SH-PTP1, PTPN6, PTP-1C, PTP1C, Protein-Tyrosine Phosphatase SHP-1, Protein-Tyrosine Phosphatase 1C, Hematopoietic Cell Protein-Tyrosine Phosphatase, HCP

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $183 | 7-10 days | 7-10 days | |
| 20 µg | $292 | 7-10 days | 7-10 days | |
| 50 µg | $545 | 7-10 days | 7-10 days | |
| 100 µg | $792 | 7-10 days | 7-10 days | |
| 200 µg | $1,150 | 7-10 days | 7-10 days | |
| 500 µg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-6xHis |
| Accession Number | P29350-3 |
| Amino Acid | Lys243-Ile541 |
| Construction | Lys243-Ile541 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 25 mM Tris-HCl, 500 mM NaCl, 2 mM 2-Mercaptoethanol, 1 mM EDTA, 1 mM DTT, 20% Glycerol, pH7.5. |
| Synonyms | Tyrosine-Protein Phosphatase Non-Receptor Type 6, SH-PTP1, PTPN6, PTP-1C, PTP1C, Protein-Tyrosine Phosphatase SHP-1, Protein-Tyrosine Phosphatase 1C, Hematopoietic Cell Protein-Tyrosine Phosphatase, HCP |
| Research Background | Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. In addition, PTP1C also modulates signaling by tyrosine phosphorylated cell surface receptors. |
| Molecular Weight | 34 KDa (reducing condition) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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