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Sotatercept (Synonyms: MK-7962, MK7962, ACE-011, ACE011)

Catalog No. T76995 Copy Product Info
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Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.

Sotatercept

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Catalog No. T76995
Synonyms MK-7962, MK7962, ACE-011, ACE011

Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.

Sotatercept
Cas No. 1001080-50-7
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$579-In Stock
5 mg$1,480-In Stock
10 mg$2,390-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97% (SDS-PAGE); 97.8% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.
In vitro
At a concentration of 100 μg/mL, Sotatercept was able to down-regulate the expression levels of VEGF, oncostatin M (OSM), IL-6, BMP-2, MMP-1 and MMP-13 secreted by stromal cells. [1]
SynonymsMK-7962, MK7962, ACE-011, ACE011
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetACVR2A
Chemical Properties
Molecular Weight38.94 kDa
Cas No.1001080-50-7
Antibody Information
IsotypeHuman IgG1 Fc
Storage & Solubility Information
StorageStore at low temperature | Shipping with blue ice/Shipping at ambient temperature.

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