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Sotatercept

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Catalog No. T76995Cas No. 1001080-50-7
Alias MK-7962, MK7962, ACE-011, ACE011

Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.

Sotatercept

Sotatercept

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Catalog No. T76995Alias MK-7962, MK7962, ACE-011, ACE011Cas No. 1001080-50-7
Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$579-In Stock
5 mg$1,480-In Stock
10 mg$2,390-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97% (SDS-PAGE); 97.8% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.
In vitro
At a concentration of 100 μg/mL, Sotatercept was able to down-regulate the expression levels of VEGF, oncostatin M (OSM), IL-6, BMP-2, MMP-1 and MMP-13 secreted by stromal cells. [1]
SynonymsMK-7962, MK7962, ACE-011, ACE011
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetACVR2A
Chemical Properties
Molecular Weight38.94 kDa
Cas No.1001080-50-7
Antibody Information
IsotypeHuman IgG1 Fc
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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