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Apilimod mesylate

🥰Excellent
Catalog No. T3533Cas No. 870087-36-8
Alias STA 5326 mesylate

Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.

Apilimod mesylate
Other Forms of Apilimod mesylate:

Apilimod mesylate

🥰Excellent
Purity: 99.7%
Catalog No. T3533Alias STA 5326 mesylateCas No. 870087-36-8
Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30In StockIn Stock
5 mg$46In StockIn Stock
10 mg$74In StockIn Stock
25 mg$94In StockIn Stock
50 mg$113In StockIn Stock
100 mg$178In StockIn Stock
200 mg$267In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.7%
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Product Introduction

Bioactivity
Description
Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.
Targets&IC50
IL-12:10 nM.
SynonymsSTA 5326 mesylate
Chemical Properties
Molecular Weight610.7
FormulaC25H34N6O8S2
Cas No.870087-36-8
SmilesCS(O)(=O)=O.CS(O)(=O)=O.Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 6.11 mg/mL (10 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.64 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6375 mL8.1873 mL16.3747 mL81.8733 mL
5 mM0.3275 mL1.6375 mL3.2749 mL16.3747 mL
10 mM0.1637 mL0.8187 mL1.6375 mL8.1873 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

STA-5326 MesylateSTA5326 MesylateSTA-5326STA5326STA 5326 MesylateSTA 5326PIKfyveInterleukin RelatedInterleukinInhibitorinhibitILReceptorIL-23IL-12IL ReceptorFab1Apilimod mesylateApilimod MesylateApilimod
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