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Hypidone hydrochloride (Alias: YL0919)

Name: Hypidone hydrochloride
Brand: TargetMol
SKU: T3648
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T3648 Copy Product Info

Purity: 99.93%

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Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor.

Hypidone hydrochloride

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Catalog No. T3648

Alias YL0919

Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor.

Cas No. 1339058-04-6

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Pack Size	Price	USA Stock	Global Stock
5 mg	$38	In Stock	In Stock
10 mg	$48	In Stock	In Stock
25 mg	$73	In Stock	In Stock
50 mg	$119	In Stock	In Stock
100 mg	$221	In Stock	In Stock
200 mg	$329	-	In Stock
1 mL x 10 mM (in DMSO)	$44	In Stock	In Stock

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.93%

Color:White

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COA

Product Introduction

Bioactivity

Description	Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor.
Targets&IC50	Human recombinant cells:1.93±0.18 nM, 5-HT uptake (rat cerebral cortical synaptosomes):1.78±0.34 nM
Synonyms	YL0919

Chemical Properties

Molecular Weight	334.84
Formula	C₁₈H₂₃ClN₂O₂
Cas No.	1339058-04-6
Smiles	Cl.OC1(Cn2ccccc2=O)CCN(Cc2ccccc2)CC1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (89.6 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (5.97 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9865 mL	14.9325 mL	29.8650 mL	149.3251 mL
5 mM	0.5973 mL	2.9865 mL	5.9730 mL	29.8650 mL
10 mM	0.2987 mL	1.4933 mL	2.9865 mL	14.9325 mL
20 mM	0.1493 mL	0.7466 mL	1.4933 mL	7.4663 mL
50 mM	0.0597 mL	0.2987 mL	0.5973 mL	2.9865 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc