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Pentoxifylline

🥰Excellent
Catalog No. T0070Cas No. 6493-05-6
Alias PTX, Oxpentifylline, BL-191

Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet aggregation and improves blood flow by increasing erythrocyte and leukocyte flexibility.

Pentoxifylline
Other Forms of Pentoxifylline:
Pentoxifylline-d6T713001185879-03-1
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Pentoxifylline

🥰Excellent
Purity: 99.93%
Catalog No. T0070Alias PTX, Oxpentifylline, BL-191Cas No. 6493-05-6
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet aggregation and improves blood flow by increasing erythrocyte and leukocyte flexibility.
Pack SizePriceAvailabilityQuantity
500 mg$40In Stock
1 g$48In Stock
5 g$113In Stock
1 mL x 10 mM (in DMSO)$44In Stock
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Purity:99.93%
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Product Introduction

Bioactivity
Description
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet aggregation and improves blood flow by increasing erythrocyte and leukocyte flexibility.
SynonymsPTX, Oxpentifylline, BL-191
Chemical Properties
Molecular Weight278.31
FormulaC13H18N4O3
Cas No.6493-05-6
SmilesO=C1C2=C(N(C)C(=O)N1CCCCC(C)=O)N=CN2C
Relative Density.1.1713 g/cm3 (Estimated)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 197.6 mM, Sonication is recommended.
DMSO: 18.33 mg/mL (65.86 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM3.5931 mL17.9656 mL35.9312 mL179.6558 mL
5 mM0.7186 mL3.5931 mL7.1862 mL35.9312 mL
10 mM0.3593 mL1.7966 mL3.5931 mL17.9656 mL
20 mM0.1797 mL0.8983 mL1.7966 mL8.9828 mL
50 mM0.0719 mL0.3593 mL0.7186 mL3.5931 mL
H2O
1mg5mg10mg50mg
100 mM0.0359 mL0.1797 mL0.3593 mL1.7966 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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