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Dihydrosinapyl alcohol

Name: Dihydrosinapyl alcohol
Brand: TargetMol
SKU: TN3866
Price: 100 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN3866Cas No. 20736-25-8

Alias Dihydrosinapylalcohol

Dihydrosinapyl alcohol (Dihydrosinapylalcohol) is a natural product from Clerodendranthus spicatus.

Dihydrosinapyl alcohol

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Purity: 99.26%

Catalog No. TN3866Alias DihydrosinapylalcoholCas No. 20736-25-8

Dihydrosinapyl alcohol (Dihydrosinapylalcohol) is a natural product from Clerodendranthus spicatus.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$34	In Stock	In Stock
25 mg	$51	In Stock	In Stock
50 mg	Preferential	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$100	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.26%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Dihydrosinapyl alcohol AI Summary

Dihydrosinapyl alcohol inhibits the PDE4D2 catalytic domain with an IC50 value greater than 20,000.0 nM, suggesting potential activity in modulating the cAMP signaling pathway. It shows antibacterial activity against Pseudomonas aeruginosa ATCC 27853 and PAO397 with inhibition percentages of 37.7% and 9.32%, respectively, and against Acinetobacter baumannii ATCC 19606 with an inhibition percentage of 1.23%. Additionally, Dihydrosinapyl alcohol inhibits the growth of Mycobacterium tuberculosis in phenotypic assays, showing a percent effect of 16.94% on DPPC, cholesterol, and tyloxapol based media for 4 days, and 25.33% on 7H9, glucose, and tyloxapol based media for 3 days. However, it shows a negative percent effect of -6.776% in an in vitro enzyme assay targeting the hydrolysis of chlorophenol red-beta-D-galactopyranosidase in Toxoplasma expressing beta-galactosidase..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Dihydrosinapyl alcohol (Dihydrosinapylalcohol) is a natural product from Clerodendranthus spicatus.
Synonyms	Dihydrosinapylalcohol

Chemical Properties

Molecular Weight	212.24
Formula	C₁₁H₁₆O₄
Cas No.	20736-25-8
Smiles	COc1cc(CCCO)cc(OC)c1O
Relative Density.	1.161g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (259.14 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.42 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.7116 mL	23.5582 mL	47.1165 mL	235.5824 mL
5 mM	0.9423 mL	4.7116 mL	9.4233 mL	47.1165 mL
10 mM	0.4712 mL	2.3558 mL	4.7116 mL	23.5582 mL
20 mM	0.2356 mL	1.1779 mL	2.3558 mL	11.7791 mL
50 mM	0.0942 mL	0.4712 mL	0.9423 mL	4.7116 mL
100 mM	0.0471 mL	0.2356 mL	0.4712 mL	2.3558 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc