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Anti-ADAMTS8 Polyclonal Antibody

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Catalog No. TMAB-00058
Alias METH8, METH2, METH 8, METH 2, ATS8, ADAMTS 8, ADAM TS8, ADAM TS 8, ADAM metallopeptidase with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8, A disintegrin and metalloproteinase with thrombospondin motifs 8

Anti-ADAMTS8 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS8. Anti-ADAMTS8 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.

Anti-ADAMTS8 Polyclonal Antibody

Anti-ADAMTS8 Polyclonal Antibody

😃Good
Catalog No. TMAB-00058Alias METH8, METH2, METH 8, METH 2, ATS8, ADAMTS 8, ADAM TS8, ADAM TS 8, ADAM metallopeptidase with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8, A disintegrin and metalloproteinase with thrombospondin motifs 8
Anti-ADAMTS8 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS8. Anti-ADAMTS8 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2227-10 days
100 μL$3737-10 days
200 μL$5287-10 days
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Product Introduction

Bioactivity
Description
Anti-ADAMTS8 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS8. Anti-ADAMTS8 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
AliasMETH8, METH2, METH 8, METH 2, ATS8, ADAMTS 8, ADAM TS8, ADAM TS 8, ADAM metallopeptidase with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease with thrombospondin type 1 motif 8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 motif 8, A disintegrin and metalloproteinase with thrombospondin motifs 8
Ig Type
IgG
Reactivity
(predicted:Human,Mouse,Rat,Chicken,Dog,Pig,Horse)
Application
WB,IHC-P,IHC-Fr,IF,ELISA
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space, extracellular matrix (By similarity).
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ADAMTS8
Antigen Species
Human
Gene ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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