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IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
(Synonyms: Mac25, insulin-like growth factor binding protein 7, Fstl2, AGM) Copy Product InfoSynonyms: Mac25, insulin-like growth factor binding protein 7, Fstl2, AGM
Catalog No. TMPY-04508 Copy Product Info
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the accession number is A0A5E1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $47 | - | In Stock | |
| 10 μg | $73 | - | In Stock | |
| 20 μg | $117 | - | In Stock | |
| 50 μg | $226 | - | In Stock | |
| 100 μg | $378 | - | In Stock | |
| 200 μg | $643 | 7-10 days | 7-10 days | |
| 500 μg | $1,310 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:93.4%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the accession number is A0A5E1. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | A0A5E1 |
| Construction | A DNA sequence encoding the mouse Igfbp7 (AAH92538.1) (Met1-Leu281) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ser 26 |
| Protein Purity | > 95 % as determined by SDS-PAGE.  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Mac25, insulin-like growth factor binding protein 7, Fstl2, AGM |
| Research Background | Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| Molecular Weight | 53.3 kDa (predicted) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) chemical structure | IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) molecular weight
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