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Anti-Haptoglobin Antibody (4J724)

(Synonyms: Zonulin, HP, Haptoglobin) Copy Product Info
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Synonyms: Zonulin, HP, Haptoglobin

Catalog No. TMAH-00565 Copy Product Info
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Anti-Haptoglobin Antibody (4J724) is an antibody targeting Haptoglobin. Anti-Haptoglobin Antibody (4J724) can be used in ELISA,IHC.
Anti-Haptoglobin Antibody
(4J724)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Haptoglobin Antibody (4J724) is an antibody targeting Haptoglobin. Anti-Haptoglobin Antibody (4J724) can be used in ELISA,IHC.
SynonymsZonulin, HP, Haptoglobin
Ig Type
Rabbit IgG
Clone
4J724
Reactivity
Human
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
Tissue SpecificityExpressed by the liver and secreted in plasma.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundAs a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. The uncleaved form of allele alpha-2 (2-2), known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Haptoglobin
Antigen Species
Human
Gene Name
HP
Gene ID
Uniprot ID
Biology Area
Cardiovascular
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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