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1-(2-Pyridylazo)-2-naphthol

Name: 1-(2-Pyridylazo)-2-naphthol
Brand: TargetMol
SKU: T9206
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9206Cas No. 85-85-8

1-(2-Pyridylazo)-2-naphthol (PAN) is a complexation index agent.

1-(2-Pyridylazo)-2-naphthol

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Purity: 99.33%

Catalog No. T9206Cas No. 85-85-8

1-(2-Pyridylazo)-2-naphthol (PAN) is a complexation index agent.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.33%

Appearance:solid

Color:Red

Resource Download

COA HNMR LCMS

Product Introduction

1-(2-Pyridylazo)-2-naphthol AI Summary

1-(2-Pyridylazo)-2-naphthol has demonstrated bioactivity across numerous assays, showing significant potency in inhibiting various enzymes and proteins. These include Lamin A splicing, Luciferase translation, Jumonji Domain Containing 2E, Huntington aggregate formation, SMN2 splice variant expression, Tyrosyl-DNA phosphodiesterase, Tau fibril formation, ROR gamma transcriptional activity, Aldehyde dehydrogenase 1, lipid storage modulation, Heat Shock Factor 1, Trypanosoma cruzi replication, IMPase, Influenza NS1 protein function, 12-hLO, and Epigenetic control. Furthermore, it affects L3MBTL1, Histone Lysine Methyltransferase G9a, DNA Polymerase Beta, Neuropeptide S receptor, Alpha-synuclein mRNA translation, and 5'UTR stem-loop driven Prion Protein mRNA translation, among others. The compound also influences cellular processes related to tau fibrillation, cell viability, and overall protein function..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

1-(2-Pyridylazo)-2-naphthol (PAN) is a complexation index agent.

Chemical Properties

Molecular Weight	249.27
Formula	C₁₅H₁₁N₃O
Cas No.	85-85-8
Smiles	Oc1ccc2ccccc2c1\N=N\c1ccccn1
Relative Density.	1.24 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/mL (110.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0117 mL	20.0586 mL	40.1171 mL	200.5857 mL
5 mM	0.8023 mL	4.0117 mL	8.0234 mL	40.1171 mL
10 mM	0.4012 mL	2.0059 mL	4.0117 mL	20.0586 mL
20 mM	0.2006 mL	1.0029 mL	2.0059 mL	10.0293 mL
50 mM	0.0802 mL	0.4012 mL	0.8023 mL	4.0117 mL
100 mM	0.0401 mL	0.2006 mL	0.4012 mL	2.0059 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc