Home Tools
Log in
Cart

pro-Beta NGF Protein, Human, Recombinant

Catalog No. TMPJ-01468
Synonyms: β-NGF, NGF, NGFB, Beta-NGF, Beta-Nerve Growth Factor, pro-Beta NGF, β-Nerve Growth Factor, pro-β NGF

The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
pro-Beta NGF Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg In stock $ 82.00
20 μg 5 days $ 133.00
50 μg 5 days $ 249.00
100 μg 5 days $ 405.00
Bulk Inquiry
Get quote
Select Batch  
Contact us for more batch information
Biological Description
Technical Params
Product Properties
Description The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
Species Human
Expression System E.coli
Tag Tag Free
Accession Number P01138
Synonyms β-NGF, NGF, NGFB, Beta-NGF, Beta-Nerve Growth Factor, pro-Beta NGF, β-Nerve Growth Factor, pro-β NGF
Amino Acid Glu19-Ala241
Construction Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl,500mM NaCl,5%Trehalose,5%Mannitol,0.01%tween80,1mM EDTA,pH8.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

pro-Beta NGF Protein, Human, Recombinant b-Nerve Growth Factor β-NGF NGF NGFB Beta-NGF Beta-Nerve Growth Factor pro-Beta NGF β-Nerve Growth Factor pro-β NGF b-NGF pro-b NGF recombinant recombinant-proteins proteins protein

 

TargetMol