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Anti-MICB Antibody-APC (3I896)
🥰Excellent
Catalog No. TMAY-01131A
Anti-MICB Antibody-APC (3I896) is a APC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-APC (3I896) can be used in FCM.
Anti-MICB Antibody-APC (3I896)
Anti-MICB Antibody-APC (3I896)
🥰Excellent
Catalog No. TMAY-01131A
Anti-MICB Antibody-APC (3I896) is a APC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-APC (3I896) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MICB Antibody-APC (3I896) is a APC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-APC (3I896) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3I896 |
| Reactivity | Human |
| Verified Activity | Analysis of anti-MICB on HeLa cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB / MIC-B (rh MICB / MIC-B; TMPY-01066; NP_005922.2; Met 1-Gly 298) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human MICB protein (TMPY-01066) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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