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Sucrose-epichlorohydrin copolymer

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Catalog No. T40311Cas No. 26873-85-8
Alias Sucrose-epichlorohydrin copolymer 400, Polysucrose 400

Sucrose-epichlorohydrin copolymer (Polysucrose 400) is a high molecular weight polymer of sucrose co-polymerized with epichlorohydrin for density gradient separation of cells, cell membranes, organelles, and viral cells and protein liqudi-liquid phase separation (LLPS).

Sucrose-epichlorohydrin copolymer

Sucrose-epichlorohydrin copolymer

🥰Excellent
Catalog No. T40311Alias Sucrose-epichlorohydrin copolymer 400, Polysucrose 400Cas No. 26873-85-8
Sucrose-epichlorohydrin copolymer (Polysucrose 400) is a high molecular weight polymer of sucrose co-polymerized with epichlorohydrin for density gradient separation of cells, cell membranes, organelles, and viral cells and protein liqudi-liquid phase separation (LLPS).
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5 g$42In Stock
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Product Introduction

Bioactivity
Description
Sucrose-epichlorohydrin copolymer (Polysucrose 400) is a high molecular weight polymer of sucrose co-polymerized with epichlorohydrin for density gradient separation of cells, cell membranes, organelles, and viral cells and protein liqudi-liquid phase separation (LLPS).
In vitro
Sucrose-epichlorohydrin copolymer is a macromolecular crowder that plays a pivotal role in promoting liquid-liquid phase separation (LLPS) of proteins. [1] Sucrose-epichlorohydrin copolymer is currently utilized in the isolation of serum and peripheral blood mononuclear cells (PBMC) from the whole blood of Parkinson's disease (PD) patients. [2]
SynonymsSucrose-epichlorohydrin copolymer 400, Polysucrose 400
Chemical Properties
Molecular Weight434.82
FormulaC15H27ClO12
Cas No.26873-85-8
SmilesClCC1CO1.OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 40 mg/mL (91.99 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.2998 mL11.4990 mL22.9980 mL114.9901 mL
5 mM0.4600 mL2.2998 mL4.5996 mL22.9980 mL
10 mM0.2300 mL1.1499 mL2.2998 mL11.4990 mL
20 mM0.1150 mL0.5750 mL1.1499 mL5.7495 mL
50 mM0.0460 mL0.2300 mL0.4600 mL2.2998 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Sucrose-epichlorohydrin copolymerSucroseepichlorohydrin copolymerSucrose epichlorohydrin copolymerFicoll 400
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