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Sucrose-epichlorohydrin copolymer

Name: Sucrose-epichlorohydrin copolymer
Brand: TargetMol
SKU: T40311
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40311Cas No. 26873-85-8

Alias Sucrose-epichlorohydrin copolymer 400, Polysucrose 400

Sucrose-epichlorohydrin copolymer (Polysucrose 400) is a high molecular weight polymer of sucrose co-polymerized with epichlorohydrin for density gradient separation of cells, cell membranes, organelles, and viral cells and protein liqudi-liquid phase separation (LLPS).

Sucrose-epichlorohydrin copolymer

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Catalog No. T40311Alias Sucrose-epichlorohydrin copolymer 400, Polysucrose 400Cas No. 26873-85-8

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 g	$42	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Sucrose-epichlorohydrin copolymer (Polysucrose 400) is a high molecular weight polymer of sucrose co-polymerized with epichlorohydrin for density gradient separation of cells, cell membranes, organelles, and viral cells and protein liqudi-liquid phase separation (LLPS).
In vitro	Sucrose-epichlorohydrin copolymer is a macromolecular crowder that plays a pivotal role in promoting liquid-liquid phase separation (LLPS) of proteins. [1] Sucrose-epichlorohydrin copolymer is currently utilized in the isolation of serum and peripheral blood mononuclear cells (PBMC) from the whole blood of Parkinson's disease (PD) patients. [2]
Synonyms	Sucrose-epichlorohydrin copolymer 400, Polysucrose 400

Chemical Properties

Molecular Weight	434.82
Formula	C₁₅H₂₇ClO₁₂
Cas No.	26873-85-8
Smiles	ClCC1CO1.OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 40 mg/mL (91.99 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.2998 mL	11.4990 mL	22.9980 mL	114.9901 mL
5 mM	0.4600 mL	2.2998 mL	4.5996 mL	22.9980 mL
10 mM	0.2300 mL	1.1499 mL	2.2998 mL	11.4990 mL
20 mM	0.1150 mL	0.5750 mL	1.1499 mL	5.7495 mL
50 mM	0.0460 mL	0.2300 mL	0.4600 mL	2.2998 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Sucrose-epichlorohydrin copolymerSucroseepichlorohydrin copolymerSucrose epichlorohydrin copolymerFicoll 400

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