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TargetMol | Compound Library

FDA-Approved Kinase Inhibitor Library

Catalog No. L1610

Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases.

Targetmol's FDA-Approved Kinase Inhibitor Library contains 325 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors,PI 3-Kinase,CaM Kinase II,JAK,PKA,CDK,JNK,PKC,CKI II,MAPK,RAF,EGFR,MEK,SAPK,GSK,MLCK,Src-family,IKK,PDGFR,VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1610

FDA-Approved Kinase Inhibitor Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 325 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
  • All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
  • Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
  • NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
EGFR
VEGFR
c-Kit
PDGFR
Endogenous Metabolite
NF-κB
JAK
Antibacterial
FGFR
c-Met/HGFR
ROS
Bcr-Abl
FLT
Parasite
Akt
Src
p38 MAPK
CDK
Antibiotic
Tyrosine Kinases
PI3K
Adrenergic Receptor
mTOR
PKC
ERK
ALK
Raf
Reactive Oxygen Species
AMPK
Potassium Channel
Ferroptosis
ROS Kinase
JNK
Mitophagy
c-RET
MEK
Influenza Virus
Microtubule Associated
HIV Protease
Virus Protease
PKA
Calcium Channel
ROCK
CaMK
Interleukin
Trk receptor
Sodium Channel
Dopamine Receptor
Caspase
Topoisomerase
SARS-CoV
IκB/IKK
5-HT Receptor
AChR
HER
COX
Bcl-2 Family
Nrf2
TNF
TAM Receptor
Histamine Receptor
GSK-3
PDE
DNA/RNA Synthesis
FAK
Antifungal
Serine/threonin kinase
HSV
Cytochromes P450
IGF-1R
P-gp
Beta Amyloid
STAT
c-Fms
Ras
BTK
HCV Protease
Dehydrogenase
Adenosine Receptor
TOPK
PAK
Aurora Kinase
MAPK
MDM-2/p53
Syk
HIF/HIF Prolyl-Hydroxylase
S1P Receptor
Kras
ROR
Ligands for Target Protein for PROTAC
Antioxidant
LPL Receptor
Reductase
NADPH
Tie-2
Glutathione Peroxidase
HBV
PPAR
Serine Protease
Serotonin Transporter
CSF-1R
IRE1
Mitochondrial Metabolism
Hexokinase
ATP Citrate Lyase
Antiviral
HSP
Ephrin Receptor
FKBP
PLK
Tyrosinase
ADC Cytotoxin
PGC-1α
Thyroid hormone receptor(THR)
Chloride channel
Proton pump
Transferase
DHFR
DNA-PK
Integrin
Estrogen/progestogen Receptor
YAP
IFNAR
gp120/CD4
Phosphatase
Progesterone Receptor
Melatonin Receptor
OCT
PARP
Antifolate
Hck
Cell Cycle Arrest
Nucleoside Antimetabolite/Analog
Glucokinase
TRP/TRPV Channel
IDO
Glucocorticoid Receptor
iGluR
Adenylate cyclase
LDL
GRK
MT Receptor
ABC Transporter
Monoamine Transporter
Opioid Receptor
IL Receptor
Cholinesterase (ChE)
Angiotensin-converting Enzyme (ACE)
MMP
Chk
Xanthine Oxidase
PAD
GluR
Lipoxygenase
Norepinephrine
DNA
Indoleamine 2,3-Dioxygenase (IDO)
TGF-beta/Smad
BCRP
Prostaglandin Receptor
TLR
Casein Kinase
GST
Retinoid Receptor
HDAC
PDK
Gap Junction Protein
NOD
IRAK
S6 Kinase
Sigma receptor
PKM
NO Synthase

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