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PS47

Name: PS47
Brand: TargetMol
SKU: T24677
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T24677Cas No. 1180676-33-8

Alias PS-47, PS 47

PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.

PS47

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Purity: 99.09%

Catalog No. T24677Alias PS-47, PS 47Cas No. 1180676-33-8

PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$41	In Stock	In Stock
25 mg	$88	In Stock	In Stock
50 mg	$138	In Stock	In Stock
100 mg	$227	In Stock	In Stock
200 mg	$321	-	In Stock
1 mL x 10 mM (in DMSO)	$41	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.09%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.
In vitro	PS47 exhibits minimal or no binding affinity to PDK1 (Kd > 200 μM)[1].
Synonyms	PS-47, PS 47

Chemical Properties

Molecular Weight	286.75
Formula	C₁₇H₁₅ClO₂
Cas No.	1180676-33-8
Smiles	OC(=O)\C=C(/CCc1ccc(Cl)cc1)c1ccccc1
Relative Density.	1.225 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (313.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4874 mL	17.4368 mL	34.8736 mL	174.3679 mL
5 mM	0.6975 mL	3.4874 mL	6.9747 mL	34.8736 mL
10 mM	0.3487 mL	1.7437 mL	3.4874 mL	17.4368 mL
20 mM	0.1744 mL	0.8718 mL	1.7437 mL	8.7184 mL
50 mM	0.0697 mL	0.3487 mL	0.6975 mL	3.4874 mL
100 mM	0.0349 mL	0.1744 mL	0.3487 mL	1.7437 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc