Shopping Cart

Your shopping cart is currently empty

PS47

Name: PS47
Brand: TargetMol
SKU: T24677
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T24677Cas No. 1180676-33-8

Alias PS-47, PS 47

PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.

PS47

Copy Product Info

😃Good

Purity: 99.09%

Catalog No. T24677Alias PS-47, PS 47Cas No. 1180676-33-8

PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$41	In Stock	In Stock
25 mg	$88	In Stock	In Stock
50 mg	$138	In Stock	In Stock
100 mg	$227	In Stock	In Stock
200 mg	$321	-	In Stock
1 mL x 10 mM (in DMSO)	$41	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.09%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.
In vitro	PS47 exhibits minimal or no binding affinity to PDK1 (Kd > 200 μM)[1].
Synonyms	PS-47, PS 47

Chemical Properties

Molecular Weight	286.75
Formula	C₁₇H₁₅ClO₂
Cas No.	1180676-33-8
Smiles	OC(=O)\C=C(/CCc1ccc(Cl)cc1)c1ccccc1
Relative Density.	1.225 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (313.86 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (11.51 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4874 mL	17.4368 mL	34.8736 mL	174.3679 mL
5 mM	0.6975 mL	3.4874 mL	6.9747 mL	34.8736 mL
10 mM	0.3487 mL	1.7437 mL	3.4874 mL	17.4368 mL
20 mM	0.1744 mL	0.8718 mL	1.7437 mL	8.7184 mL
50 mM	0.0697 mL	0.3487 mL	0.6975 mL	3.4874 mL
100 mM	0.0349 mL	0.1744 mL	0.3487 mL	1.7437 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc