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Sodium 2-mercaptoethanesulfonate

🥰Excellent
Catalog No. T1414Cas No. 19767-45-4
Alias Uromitexan, Mitexan, Mesnum, Mesnex, Mesna

Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.

Sodium 2-mercaptoethanesulfonate

Sodium 2-mercaptoethanesulfonate

🥰Excellent
Purity: 99.89%
Catalog No. T1414Alias Uromitexan, Mitexan, Mesnum, Mesnex, MesnaCas No. 19767-45-4
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
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Purity:99.89%
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Product Introduction

Bioactivity
Description
Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
SynonymsUromitexan, Mitexan, Mesnum, Mesnex, Mesna
Chemical Properties
Molecular Weight164.18
FormulaC2H5NaO3S2
Cas No.19767-45-4
Smiles[Na+].[O-]S(=O)(=O)CCS
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 55 mg/mL (335 mM), Sonication is recommended.
H2O: 7 mg/mL (42.64 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM6.0909 mL30.4544 mL60.9088 mL304.5438 mL
5 mM1.2182 mL6.0909 mL12.1818 mL60.9088 mL
10 mM0.6091 mL3.0454 mL6.0909 mL30.4544 mL
20 mM0.3045 mL1.5227 mL3.0454 mL15.2272 mL
DMSO
1mg5mg10mg50mg
50 mM0.1218 mL0.6091 mL1.2182 mL6.0909 mL
100 mM0.0609 mL0.3045 mL0.6091 mL3.0454 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

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