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2'-Deoxycytidine-5'-monophosphoric acid
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Catalog No. T4731Cas No. 1032-65-1
Alias dCMP, 2'-Deoxycytidine 5'-monophosphate
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) that forms dCDP, which, upon phosphorylation to dCTP, supports DNA biosynthesis.
2'-Deoxycytidine-5'-monophosphoric acid
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Purity: 99.02%
Catalog No. T4731Alias dCMP, 2'-Deoxycytidine 5'-monophosphateCas No. 1032-65-1
2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) that forms dCDP, which, upon phosphorylation to dCTP, supports DNA biosynthesis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $29 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.02%
Color:White
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Product Introduction
2'-Deoxycytidine-5'-monophosphoric acid AI Summary
2'-Deoxycytidine-5'-monophosphoric acid is involved in bioactivities related to both YMPK activity expressed in Huh7 cells and deoxycytidylate deaminase activity in human HepG2 cells. In Huh7 cells, the compound influences the ratio of Kcat to Km for YMPK activity, with specific attention to phosphorylation as assessed through a coupled enzyme assay. For deoxycytidylate deaminase, the enzyme activity in HepG2 cells shows a Kcat value of 246.0 /s and a Km value of 87000.0 nM, resulting in a catalytic efficiency (Kcat/Km) of 2.8 /uM/s. These values highlight the compound's impact on the catalytic efficiency and substrate binding affinity of both enzymes..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) that forms dCDP, which, upon phosphorylation to dCTP, supports DNA biosynthesis. |
| Synonyms | dCMP, 2'-Deoxycytidine 5'-monophosphate |
| Molecular Weight | 307.2 |
| Formula | C9H14N3O7P |
| Cas No. | 1032-65-1 |
| Smiles | Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)c(=O)n1 |
| Relative Density. | 2.01 g/cm3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: Slightly soluble  H2O: 6.25 mg/mL (20.35 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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