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Pinoresinol dimethyl ether

🥰Excellent
Catalog No. T2S0531Cas No. 29106-36-3
Alias (+)-Eudesmin

Pinoresinol dimethyl ether is a nonphenolic furan lignan isolated from the stem bark of Magnolia kobus with neurological activity. It stimulates upstream MAPK, PKC and PKA pathways and induces neural protrusion growth in PC12 cells.

Pinoresinol dimethyl ether
Other Forms of Pinoresinol dimethyl ether:

Pinoresinol dimethyl ether

🥰Excellent
Purity: 99.75%
Catalog No. T2S0531Alias (+)-EudesminCas No. 29106-36-3
Pinoresinol dimethyl ether is a nonphenolic furan lignan isolated from the stem bark of Magnolia kobus with neurological activity. It stimulates upstream MAPK, PKC and PKA pathways and induces neural protrusion growth in PC12 cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$31In StockIn Stock
5 mg$68In StockIn Stock
10 mg$98In StockIn Stock
25 mg$162In StockIn Stock
50 mg$238In StockIn Stock
100 mg$357-In Stock
1 mL x 10 mM (in DMSO)$76In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.75%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Pinoresinol dimethyl ether is a nonphenolic furan lignan isolated from the stem bark of Magnolia kobus with neurological activity. It stimulates upstream MAPK, PKC and PKA pathways and induces neural protrusion growth in PC12 cells.
Synonyms(+)-Eudesmin
Chemical Properties
Molecular Weight386.44
FormulaC22H26O6
Cas No.29106-36-3
Smiles[H][C@]12CO[C@H](c3ccc(OC)c(OC)c3)[C@@]1([H])CO[C@@H]2c1ccc(OC)c(OC)c1
Relative Density.1.173 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (142.32 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.18 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5877 mL12.9386 mL25.8772 mL129.3862 mL
5 mM0.5175 mL2.5877 mL5.1754 mL25.8772 mL
10 mM0.2588 mL1.2939 mL2.5877 mL12.9386 mL
20 mM0.1294 mL0.6469 mL1.2939 mL6.4693 mL
50 mM0.0518 mL0.2588 mL0.5175 mL2.5877 mL
100 mM0.0259 mL0.1294 mL0.2588 mL1.2939 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PKCPinoresinol dimethyl etherInhibitorinhibitEudesmin
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