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D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 mg | $31 | In Stock | In Stock | |
| 1 g | $38 | In Stock | In Stock | |
| 1 mL x 10 mM (in H2O) | $39 | In Stock | In Stock |
| Description | D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine). |
| In vitro | Aspirin (oral administration of 200 mg/kg) co-administered with D-phenylalanine (oral administration of 500 mg/kg) rather than with sodium zomepirac (oral administration of 200 mg/kg) resulted in a statistically significant minor increase in the aversion threshold. The oral administration of 500 mg/kg D-Phenylalanine alone caused a minor, statistically insignificant increase in the aversion threshold that was not reversed by naloxone. |
| In vivo | D-Phenylalanine binds to carboxypeptidase A by disrupting the functional active site at Glu-270 and the hydrogen bonds between zinc-bound water molecules, facilitating the displacement of metal-bound water anions. |
| Molecular Weight | 165.19 |
| Formula | C9H11NO2 |
| Cas No. | 673-06-3 |
| Smiles | N[C@H](Cc1ccccc1)C(O)=O |
| Relative Density. | 1.1603 g/cm3 (Estimated) |
| Storage | keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: Insoluble H2O: 10 mM, Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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