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IL-33 Protein, Rhesus macaque, Recombinant (His)
(Synonyms: Nuclear Factor From High Endothelial Venules, NF-HEV, NFHEV, Interleukin-33, Interleukin-1 Family Member 11, IL-33, IL33, IL-1F11, IL1F11, C9orf26) Copy Product InfoSynonyms: Nuclear Factor From High Endothelial Venules, NF-HEV, NFHEV, Interleukin-33, Interleukin-1 Family Member 11, IL-33, IL33, IL-1F11, IL1F11, C9orf26
Catalog No. TMPJ-00617 Copy Product Info
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 35 days | 35 days | |
| 10 μg | $183 | 35 days | 35 days | |
| 20 μg | $292 | 35 days | 35 days | |
| 50 μg | $545 | 35 days | 35 days | |
| 100 μg | $813 | 35 days | 35 days | |
| 200 μg | $1,190 | 35 days | 35 days | |
| 500 μg | $2,070 | 35 days | 35 days | |
| 1 mg | $2,970 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells. |
| Species | Rhesus |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | F7DLG4 |
| Amino Acid | Ser112-Ile270 |
| Construction | Ser112-Ile270 |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Nuclear Factor From High Endothelial Venules, NF-HEV, NFHEV, Interleukin-33, Interleukin-1 Family Member 11, IL-33, IL33, IL-1F11, IL1F11, C9orf26 |
| Research Background |
| Molecular Weight | 21 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: IL-33 Protein, Rhesus macaque, Recombinant (His) chemical structure | IL-33 Protein, Rhesus macaque, Recombinant (His) molecular weight
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