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4-Pentynoic acid (Propargylacetic acid) reacts with 1-bromo-1-alkynes in the presence of a Pd catalyst to yield biologically active ynenol lactones and is used in the synthesis of a cytotoxic macrolide via ring-closing metathesis of a bis acetylene.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $29 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock |
| Description | 4-Pentynoic acid (Propargylacetic acid) reacts with 1-bromo-1-alkynes in the presence of a Pd catalyst to yield biologically active ynenol lactones and is used in the synthesis of a cytotoxic macrolide via ring-closing metathesis of a bis acetylene. |
| Synonyms | Propargylacetic acid |
| Molecular Weight | 98.1 |
| Formula | C5H6O2 |
| Cas No. | 6089-09-4 |
| Smiles | OC(=O)CCC#C |
| Relative Density. | 1.096g/cm3 |
| Color | White |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (458.72 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (10.19 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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