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Description | S-acetyl-PEG4-Boc, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, consisting of two ligands linked together—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 380.5 |
Formula | C17H32O7S |
Cas No. | 1818294-26-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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