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Microbiology/Virology ribosome

ribosome

Ribosomes are macromolecular machines, found within all living cells, that perform biological protein synthesis (mRNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA (mRNA) molecules to form polypeptide chains. Ribosomes consist of two major components: the small and large ribosomal subunits. Each subunit consists of one or more ribosomal RNA (rRNA) molecules and many ribosomal proteins (RPs or r-proteins). The ribosomes and associated molecules are also known as the translational apparatus.
Cat No. product name
T4222 KKL10 KKL-10, a ribosome rescue inhibitor, has broad-spectrum antimicrobial activity against bacteria.
T1022 Hygromycin B Hygromycin B inhibits protein synthesis by disturbing with translocation and causing mistranslation at the 70S ribosome. Hygromycin b is used as an anthelmintic ...
T1419 Azithromycin dihydrate Azithromycin dihydrate is a semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium in...
T0474 Erythromycin ethylsuccinate Erythromycin ethylsuccinate is a macrolide antibiotic, produced by Streptomyces erythreus.
T0950 Neomycin sulfate Neomycin is a broad spectrum aminoglycoside antibiotic whose current use is limited to oral and topical administration.
T1441 Capastat sulfate Capreomycin Sulfate, a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis.
T1326 Gentamycin sulfate Gentamycin Sulfate is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.
T3125 Amikacin Sulfate Salt Amikacin Sulfate Salt is a broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and ototoxic like the other aminoglycoside antibiotics.
T0788 Spectinomycin dihydrochloride Spectinomycin hydrochloride anhydrous is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatme...
T1569 Tigecycline Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the ...
T0788L Spectinomycin dihydrochloride pentahydrate Spectinomycin dihydrochloride pentahydrate is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the tr...
T6638 Retapamulin Retapamulin, a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM).
T1687L Doxycycline hyclate Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity. It is also an inhibitor of matrix metalloproteinases (MMP).
T1142 Clindamycin phosphate Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lin...
T1557 Acetylspiramycin Acetylspiramycin targets 50S ribosome to inhibit protein synthesis.
T0793 Kanamycin sulfate Kanamycin sulfate is an aminoglycoside bacteriocidal antibiotic.
T1255 Tobramycin Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.
T1277 Lincomycin hydrochloride Lincomycin Hydrochloride Anhydrous is the anhydrous hydrochloride salt form of lincomycin, a lincosamide antibiotic originally identified in actinomycete Strepto...
T1304 Chlortetracycline hydrochloride Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride is bacteriostatic...
T1434 Clarithromycin Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, a...
T1151 Roxithromycin Roxithromycin is a semi-synthetic derivative of the macrolide antibiotic erythromycin with antibacterial and anti-malarial activities.
T0895 Oxytetracycline Oxytetracycline is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
T1235 Lincomycin hydrochloride monohydrate Lincomycin hydrochloride is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptoco...
T0912 Tetracycline hydrochloride Tetracycline Hydrochloride is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycli...
T1400 Demeclocycline hydrochloride Demeclocycline hydrochloride is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effect...
T0971 Dirithromycin Dirithromycin is a macrolide glycopeptide antibiotic. It is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsilliti...
T1013 Amikacin Amikacin is a broad-spectrum antibiotic derived from kanamycin.
T0912L Tetracycline Tetracycline is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
T2219 Puromycin dihydrochloride Puromycin hydrochloride is a cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and ...
T1205 Chloramphenicol Chloramphenicol, a broad-spectrum antibiotic, blocks bacterial protein synthesis.
T1687 Doxycycline Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity.
T0518 Methacycline hydrochloride Methacycline hydrochloride is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels f...
T0060 Streptomycin sulfate Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
T1032 Erythromycin Erythromycin is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.
KKL10
T4222CAS 952849-76-2
KKL-10, a ribosome rescue inhibitor, has broad-spectrum antimicrobial activity against bacteria.
Hygromycin B
T1022CAS 31282-04-9
Hygromycin B inhibits protein synthesis by disturbing with translocation and causing mistranslation at the 70S ribosome. Hygromycin b is used as an anthelmintic ...
Azithromycin dihydrate
T1419CAS 117772-70-0
Azithromycin dihydrate is a semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium in...
Erythromycin ethylsuccinate
T0474CAS 1264-62-6
Erythromycin ethylsuccinate is a macrolide antibiotic, produced by Streptomyces erythreus.
Neomycin sulfate
T0950CAS 1405-10-3
Neomycin is a broad spectrum aminoglycoside antibiotic whose current use is limited to oral and topical administration.
Capastat sulfate
T1441CAS 1405-37-4
Capreomycin Sulfate, a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis.
Gentamycin sulfate
T1326CAS 1405-41-0
Gentamycin Sulfate is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.
Amikacin Sulfate Salt
T3125CAS 149022-22-0
Amikacin Sulfate Salt is a broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and ototoxic like the other aminoglycoside antibiotics.
Spectinomycin dihydrochloride
T0788CAS 21736-83-4
Spectinomycin hydrochloride anhydrous is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatme...
Tigecycline
T1569CAS 220620-09-7
Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the ...
Spectinomycin dihydrochloride pentahydrate
T0788LCAS 22189-32-8
Spectinomycin dihydrochloride pentahydrate is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the tr...
Retapamulin
T6638CAS 224452-66-8
Retapamulin, a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM).
Doxycycline hyclate
T1687LCAS 24390-14-5
Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity. It is also an inhibitor of matrix metalloproteinases (MMP).
Clindamycin phosphate
T1142CAS 24729-96-2
Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lin...
Acetylspiramycin
T1557CAS 24916-51-6
Acetylspiramycin targets 50S ribosome to inhibit protein synthesis.
Kanamycin sulfate
T0793CAS 25389-94-0
Kanamycin sulfate is an aminoglycoside bacteriocidal antibiotic.
Tobramycin
T1255CAS 32986-56-4
Tobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.
Lincomycin hydrochloride
T1277CAS 859-18-7
Lincomycin Hydrochloride Anhydrous is the anhydrous hydrochloride salt form of lincomycin, a lincosamide antibiotic originally identified in actinomycete Strepto...
Chlortetracycline hydrochloride
T1304CAS 64-72-2
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride is bacteriostatic...
Clarithromycin
T1434CAS 81103-11-9
Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, a...
Roxithromycin
T1151CAS 80214-83-1
Roxithromycin is a semi-synthetic derivative of the macrolide antibiotic erythromycin with antibacterial and anti-malarial activities.
Oxytetracycline
T0895CAS 79-57-2
Oxytetracycline is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
Lincomycin hydrochloride monohydrate
T1235CAS 7179-49-9
Lincomycin hydrochloride is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptoco...
Tetracycline hydrochloride
T0912CAS 64-75-5
Tetracycline Hydrochloride is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycli...
Demeclocycline hydrochloride
T1400CAS 64-73-3
Demeclocycline hydrochloride is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effect...
Dirithromycin
T0971CAS 62013-04-1
Dirithromycin is a macrolide glycopeptide antibiotic. It is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsilliti...
Amikacin
T1013CAS 37517-28-5
Amikacin is a broad-spectrum antibiotic derived from kanamycin.
Tetracycline
T0912LCAS 60-54-8
Tetracycline is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
Puromycin dihydrochloride
T2219CAS 58-58-2
Puromycin hydrochloride is a cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and ...
Chloramphenicol
T1205CAS 56-75-7
Chloramphenicol, a broad-spectrum antibiotic, blocks bacterial protein synthesis.
Doxycycline
T1687CAS 564-25-0
Doxycycline is a synthetic tetracycline derivative with similar antimicrobial activity.
Methacycline hydrochloride
T0518CAS 3963-95-9
Methacycline hydrochloride is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels f...
Streptomycin sulfate
T0060CAS 3810-74-0
Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Erythromycin
T1032CAS 114-07-8
Erythromycin is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.