ECM1 Protein, Human, Recombinant (His)

Name: ECM1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07013
Price: 653 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: URBWD) Copy Product Info

Synonyms: URBWD

Catalog No. TMPY-07013 Copy Product Info

ECM1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q16610-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$63	-	In Stock
10 µg	$98	-	In Stock
20 µg	$163	-	In Stock
50 µg	$345	-	In Stock
100 µg	$653	7-10 days	7-10 days
200 µg	Inquiry	7-10 days	7-10 days
500 µg	Inquiry	7-10 days	7-10 days
1 mg	Inquiry	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:≥ 90 % as determined by SDS-PAGE

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	ECM1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q16610-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q16610-1
Construction	A DNA sequence encoding the human ECM1 isoform 1 (NP_004416.2)(Met 1-Glu 540) was expressed with a C-terminal polyhistidine tag.
Protein Purity	≥ 90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, pH 7.2. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	URBWD
Research Background	Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.

Chemical Properties

Molecular Weight

60.2 kDa (predicted); 80-90 kDa (reducing contition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.