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Pimicotinib

Name: Pimicotinib
Brand: TargetMol
SKU: T79157
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T79157Cas No. 2253123-16-7

Alias ABSK-021, ABSK021

Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.

Pimicotinib

🥰Excellent

Purity: 99.8%

Catalog No. T79157Alias ABSK-021, ABSK021Cas No. 2253123-16-7

Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.

Pack Size	Price	Availability
1 mg	$50	In Stock
5 mg	$118	In Stock
10 mg	$188	In Stock
25 mg	$363	In Stock
50 mg	$583	In Stock
100 mg	$935	In Stock
200 mg	$1,260	In Stock
1 mL x 10 mM (in DMSO)	$166	In Stock

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Batch Information

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Purity:99.8%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.
Synonyms	ABSK-021, ABSK021

Chemical Properties

Molecular Weight	420.46
Formula	C₂₂H₂₄N₆O₃
Cas No.	2253123-16-7
Smiles	O=C(NC=1N=C(C(OC2=CC=NC(=C2)C=3C=NN(C3)C)=CC1)C)N4C(=O)C(C)(C)CC4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (118.92 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3783 mL	11.8917 mL	23.7835 mL	118.9174 mL
5 mM	0.4757 mL	2.3783 mL	4.7567 mL	23.7835 mL
10 mM	0.2378 mL	1.1892 mL	2.3783 mL	11.8917 mL
20 mM	0.1189 mL	0.5946 mL	1.1892 mL	5.9459 mL
50 mM	0.0476 mL	0.2378 mL	0.4757 mL	2.3783 mL
100 mM	0.0238 mL	0.1189 mL	0.2378 mL	1.1892 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc