Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2 (Synonyms: v-rel avian reticuloendotheliosis viral oncogen...)
Catalog No. TMAC-02791 Copy Product Info
🥰Excellent
Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NF-kB p65 (Ser281). Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody can be used in WB.
Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAC-02791
Synonyms v-rel avian reticuloendotheliosis viral oncogene homolog A, p-NF-kB p65 (Ser281), p-NF-kB p65 (S281), p65, NFKB3, NF-kB p65 (p-Ser281), NF-kB p65 (p-S281)
Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NF-kB p65 (Ser281). Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody can be used in WB.
Anti-Phospho-NF-kB p65
(Ser281) Polyclonal Antibody 2
(Ser281) Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NF-kB p65 (Ser281). Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody can be used in WB. |
| Synonyms | v-rel avian reticuloendotheliosis viral oncogene homolog A, p-NF-kB p65 (Ser281), p-NF-kB p65 (S281), p65, NFKB3, NF-kB p65 (p-Ser281), NF-kB p65 (p-S281) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from mouse brain tissue using NF- kappaB p65 antibody TMAC-02791. The lane on the right is treated with the antigen-specific peptide.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and p65-c-Rel complexes are transcriptional activators. The NF-kappa-B p65-p65 complex appears to be involved in invasin-mediated activation of IL-8 expression. The inhibitory effect of I-kappa-B upon NF-kappa-B the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine281(E-L-S(p)-E-P) derived from Human NF- kappaB |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Keywords
Preview
Related Tags: buy Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2 | purchase Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2 | Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2 cost | order Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2 | Anti-Phospho-NF-kB p65 (Ser281) Polyclonal Antibody 2 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.