Shopping Cart
- Remove All
 
Your shopping cart is currently empty
Anti-TROP-2 Antibody-PE (7D257) is a PE-conjugated Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody-PE (7D257) can be used in FCM.
| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 25 T | $105 | 7-10 days | |
| 100 T | $327 | 7-10 days | 
| Description | Anti-TROP-2 Antibody-PE (7D257) is a PE-conjugated Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody-PE (7D257) can be used in FCM.  | 
| Synonyms | tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1 | 
| Ig Type | Mouse IgG1  | 
| Clone | 7D257  | 
| Reactivity | Human  | 
| Specificity | Human TROP-2  | 
| Verified Activity | Flow cytometric analysis of anti-human TROP2 on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with PE Mouse anti-human TROP2.  | 
| Application | |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml  | 
| Antibody Type | Monoclonal  | 
| Host Species | Mouse | 
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TROP-2 / TACSTD2 (rh TROP-2 / TACSTD2; TMPY-01262; NP_002344.2; Met1-Thr274) and conjugated with PE under optimum conditions, the unreacted PE was removed. | 
| Purification | Protein A | 
| Appearance | Liquid | 
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 | 
| Research Background | TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate. | 
| Conjucates | PE  | 
| Others Formats | Unconjugated/Biotin/FITC/HRP  | 
| Antibody Types Available | 5  | 
| Immunogen | Recombinant Protein: Human TROP-2 / TACSTD2 protein (TMPY-01262)  | 
| Antigen Species | Human  | 
| Biology Area | Cancer Drug Targets  | 
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. | 
| Transport | Shipping with blue ice. | 

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.