store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 33.00 | |
10 mg | Inquiry | $ 47.00 | |
25 mg | Inquiry | $ 77.00 | |
50 mg | Inquiry | $ 115.00 | |
100 mg | Inquiry | $ 182.00 | |
200 mg | Inquiry | $ 271.00 |
Description | NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] . |
Synonyms | NH2-PEG2-C6-Cl |
Molecular Weight | 223.74 |
Formula | C10H22ClNO2 |
CAS No. | 744203-60-9 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (402.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NH2-PEG2-C6-Cl 744203-60-9 PROTAC PROTAC Linker NH2 PEG2 C6 Cl NH-2-PEG2-C6-Cl NH2PEG2C6Cl inhibitor inhibit