Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

NH2-PEG2-C6-Cl

Name: NH2-PEG2-C6-Cl
Brand: TargetMol
SKU: T40858
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T40858Cas No. 744203-60-9

Alias NH2-PEG2-C6-Cl

NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH2-PEG2-C6-Cl

😃Good

Catalog No. T40858Alias NH2-PEG2-C6-ClCas No. 744203-60-9

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$33	Inquiry	Inquiry
10 mg	$47	Inquiry	Inquiry
25 mg	$77	Inquiry	Inquiry
50 mg	$115	Inquiry	Inquiry
100 mg	$182	Inquiry	Inquiry
200 mg	$271	Inquiry	Inquiry

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	NH2-PEG2-C6-Cl is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
In vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .
Synonyms	NH2-PEG2-C6-Cl

Chemical Properties

Molecular Weight	223.74
Formula	C₁₀H₂₂ClNO₂
Cas No.	744203-60-9
Smiles	C(OCCOCCN)CCCCCCl

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (402.25 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4695 mL	22.3474 mL	44.6947 mL	223.4737 mL
5 mM	0.8939 mL	4.4695 mL	8.9389 mL	44.6947 mL
10 mM	0.4469 mL	2.2347 mL	4.4695 mL	22.3474 mL
20 mM	0.2235 mL	1.1174 mL	2.2347 mL	11.1737 mL
50 mM	0.0894 mL	0.4469 mL	0.8939 mL	4.4695 mL
100 mM	0.0447 mL	0.2235 mL	0.4469 mL	2.2347 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc