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Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs that connects two critical ligands essential for creating PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Ms-PEG5-t-butyl ester is a PEG-based linker for PROTACs that connects two critical ligands essential for creating PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize a linker to connect two distinct ligands: one for an E3 ubiquitin ligase and the other for the target protein. They selectively degrade target proteins by harnessing the intracellular ubiquitin-proteasome system[1]. |
Alias | Ms-PEG4-t-butyl ester |
Molecular Weight | 400.49 |
Formula | C16H32O9S |
Cas No. | 870487-48-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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