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Anti-Phospho-CaMK2 (Thr286) Antibody (9U416) is a Mouse antibody targeting Phospho-CaMK2 (Thr286). Anti-Phospho-CaMK2 (Thr286) Antibody (9U416) can be used in WB,IP,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-Phospho-CaMK2 (Thr286) Antibody (9U416) is a Mouse antibody targeting Phospho-CaMK2 (Thr286). Anti-Phospho-CaMK2 (Thr286) Antibody (9U416) can be used in WB,IP,IF. |
Reactivity | Rat |
Application | |
Recommended Dose | WB: 1:100-1000; IHC: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein (1ml of cell lysate) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/ threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated α, β,γandδ, which may or may not be coexpressed in the same tissue types. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177. |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide |
Uniprot ID |
Molecular Weight | Theoretical: 50 kDa. |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
Transport | Shipping with blue ice. |
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