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Human PD-L1 inhibitor I

Catalog No. T39591 CAS 2135542-86-6

Synonyms: Human PD-L1 inhibitor I

Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 inhibitor I disrupts the binding between human PD-L1 and human PD-1, thereby attenuating their respective functions.

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Human PD-L1 inhibitor I Chemical Structure

Human PD-L1 inhibitor I, CAS 2135542-86-6

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Human PD-L1 inhibitor I
Molecular Weight	2350.576
Formula	C110H152N26O32
CAS No.	2135542-86-6

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Tianyu Wang, et al. Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway. J Med Chem. 2019 Feb 28;62(4):1715-1730.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Human PD-L1 inhibitor I 2135542-86-6 Human PD L1 inhibitor I Human PD-L-1 inhibitor I Human PDL1 inhibitor I inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.