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Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $30 | In Stock | In Stock | |
| 25 mg | $51 | In Stock | In Stock | |
| 50 mg | $81 | In Stock | In Stock | |
| 100 mg | $117 | In Stock | In Stock | |
| 200 mg | $173 | - | In Stock |
| Description | Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. |
| Targets&IC50 | Leishmania infantum:2.5 μM (IC50) |
| In vitro | Pentamidine is effective in therapy for the hemolymphatic stage of Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia[1]. |
| Molecular Weight | 340.42 |
| Formula | C19H24N4O2 |
| Cas No. | 100-33-4 |
| Smiles | C(=N)(N)C1=CC=C(OCCCCCOC2=CC=C(C(=N)N)C=C2)C=C1 |
| Relative Density. | 1.2g/cm3 |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Slightly soluble |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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