FGF-21 Protein, Human, Recombinant

Name: FGF-21 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPS-00173
Rating: 4.5 (1 reviews)

(Synonyms: fibroblast growth factor-21, FGFL, FGF21) Copy Product Info

Synonyms: fibroblast growth factor-21, FGFL, FGF21

Catalog No. TMPS-00173 Copy Product Info

FGF-21 Protein, Human, Recombinant is expressed in E. coli. The accession number is Q9NSA1.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$85	7-10 days	7-10 days
10 µg	$138	7-10 days	7-10 days
20 µg	$197	7-10 days	7-10 days
50 µg	$339	7-10 days	7-10 days
100 µg	$573	7-10 days	7-10 days
200 µg	$977	7-10 days	7-10 days
500 µg	$1,980	7-10 days	7-10 days
1 mg	$3,390	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 0.5 µg/ml, measured by a cell proliferation assay using NIH-3T3 cells in the presence of 1.25 µg/ml mouse Klotho and 10 µg/ml heparin, corresponding to a specific activity of > 2.0 × 10 3 units/mg.
Description	FGF-21 Protein, Human, Recombinant is expressed in E. coli. The accession number is Q9NSA1.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	Q9NSA1
Construction	His29-Ser209
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	fibroblast growth factor-21, FGFL, FGF21
Research Background	Fibroblast Growth Factor-21 (FGF-21) is a metabolic cytokine belonging to the heparin-binding FGF family. Along with FGF-19/15 and FGF-23, FGF-21 is categorized as a member of the atypical FGF subfamily, as it must be complexed to the Klotho co-receptor in order to bind to the FGF receptors and activate the downstream signaling pathway. In vivo FGF-21 is expressed in liver, pancreas, adipose tissue, and skeletal muscle, and it plays a central role in the energy metabolism. The expression of FGF-21 is stimulated by free fatty acids and insulin resistant states and is correlated with whole-body insulin resistance. FGF-21 activates glucose uptake in adipocytes and increases insulin sensitivity, implicating it as a novel target with potential anti-diabetic properties.

Chemical Properties

Molecular Weight

~19.5 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.