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MGAT2 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01092
Synonyms: Alpha-1, Mannoside Acetylglucosaminyltransferase 2, 6-Mannosyl-Glycoprotein 2-β-N-Acetylglucosaminyltransferase, NT-II, GlcNAc-T II, 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase, 2-N-acetylglucosaminyltransferase II, β-1, Beta-1, N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II, α-1

Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

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MGAT2 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number Q10469
Synonyms Alpha-1, Mannoside Acetylglucosaminyltransferase 2, 6-Mannosyl-Glycoprotein 2-β-N-Acetylglucosaminyltransferase, NT-II, GlcNAc-T II, 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase, 2-N-acetylglucosaminyltransferase II, β-1, Beta-1, N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II, α-1
Amino Acid Arg30-Gln447
Construction Recombinant Human Mannoside Acetylglucosaminyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Arg30-Gln447 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 50 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

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Keywords

MGAT2 Protein, Human, Recombinant (His) Alpha-1 b-1 Mannoside Acetylglucosaminyltransferase 2 6-Mannosyl-Glycoprotein 2-β-N-Acetylglucosaminyltransferase NT-II GlcNAc-T II 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase a-1 2-N-acetylglucosaminyltransferase II β-1 Beta-1 N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II α-1 recombinant recombinant-proteins proteins protein

 

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