Anti-Iba1 Antibody (3Y490)

Name: Anti-Iba1 Antibody (3Y490)
Brand: TargetMol
SKU: TMAY-02698
Rating: 4.5 (1 reviews)

(Synonyms: IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1) Copy Product Info

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Synonyms: IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1

Catalog No. TMAY-02698 Copy Product Info

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Anti-Iba1 Antibody (3Y490) is a Rabbit antibody targeting Iba1. Anti-Iba1 Antibody (3Y490) can be used in ELISA,ICC/IF,IHC-P.

Anti-Iba1 Antibody
(3Y490)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$93	7-10 days	7-10 days
100 μL	$269	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Description	Anti-Iba1 Antibody (3Y490) is a Rabbit antibody targeting Iba1. Anti-Iba1 Antibody (3Y490) can be used in ELISA,ICC/IF,IHC-P.
Synonyms	IRT-1, IRT1, IBA1, allograft inflammatory factor 1, AIF-1
Ig Type	Rabbit IgG
Clone	3Y490
Reactivity	Human
Specificity	Human Iba1

Application	ELISA ICC/IF IHC-P
Recommended Dose	ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human IBA1 / AIF1 (rh IBA1 / AIF1; TMPY-03337; P55008-1; Met1-Pro147).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human IBA1 / AIF1 Protein (TMPY-03337)
Antigen Species	Human
Biology Area	Calcium-binding Proteins and Related Molecules

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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