IL-20RB Protein, Human, Recombinant (hFc)

Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

Pack Size	Availability	Price/USD
10 μg	5 days	$ 116.00
50 μg	5 days	$ 310.00
500 μg	5 days	$ 1,390.00
1 mg	5 days	$ 1,980.00

Pack Size

Availability

Price/USD

Quantity

10 μg

5 days

$ 116.00

50 μg

5 days

$ 310.00

500 μg

5 days

$ 1,390.00

1 mg

5 days

$ 1,980.00

Description

Species	Human
Expression System	Human Cells
Tag	C-Fc
Accession Number	Q6UXL0
Synonyms	DIRS1, IL-20R-β, Interleukin-20 receptor subunit β, IL-20 receptor subunit beta, IL-20RB, interleukin-20 receptor II, hCG_2022374, fibronectin type III domain containing 6, IL-20 receptor subunit β, Interleukin-20 receptor subunit beta, MGC34923, FNDC6, IL-20R-beta, IL-20R2
Amino Acid	Asp30-Ala230
Construction	Recombinant Human Interleukin-20 Receptor Subunit Beta/IL-20RB is produced by our Mammalian expression system and the target gene encoding Asp30-Ala230 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	60-85 KDa, reducing conditions

Endotoxin	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Stability & Storage	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping	The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Research Background	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

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IL-20RB Protein, Human, Recombinant (hFc)

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