IL-20RB Protein, Human, Recombinant (hFc)

Name: IL-20RB Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00194
Rating: 4.5 (1 reviews)

(Synonyms: MGC34923, Interleukin-20 receptor subunit β, Interleukin-20 receptor subunit beta, interleukin-20 receptor II, IL-20R-β, IL-20R-beta, IL-20RB, IL-20R2, IL-20 receptor subunit β, IL-20 receptor subunit beta, hCG_2022374, FNDC6, fibronectin type III domain containing 6, DIRS1) Copy Product Info

Synonyms: MGC34923, Interleukin-20 receptor subunit β, Interleukin-20 receptor subunit beta, interleukin-20 receptor II, IL-20R-β, IL-20R-beta, IL-20RB, IL-20R2, IL-20 receptor subunit β, IL-20 receptor subunit beta, hCG_2022374, FNDC6, fibronectin type III domain containing 6, DIRS1

Catalog No. TMPJ-00194 Copy Product Info

Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

IL-20RB Protein, Human, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
10 µg	$116	35 days	35 days
20 µg	$176	35 days	35 days
50 µg	$310	35 days	35 days
100 µg	$485	35 days	35 days
200 µg	$762	35 days	35 days
500 µg	$1,390	35 days	35 days
1 mg	$1,980	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q6UXL0
Amino Acid	Asp30-Ala230
Construction	Asp30-Ala230
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Synonyms	MGC34923, Interleukin-20 receptor subunit β, Interleukin-20 receptor subunit beta, interleukin-20 receptor II, IL-20R-β, IL-20R-beta, IL-20RB, IL-20R2, IL-20 receptor subunit β, IL-20 receptor subunit beta, hCG_2022374, FNDC6, fibronectin type III domain containing 6, DIRS1
Research Background	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family.

Chemical Properties

Molecular Weight

60-85 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.