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Anti-CSF3R/G-CSFR Polyclonal Antibody is a Rabbit antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-CSF3R/G-CSFR Polyclonal Antibody is a Rabbit antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Polyclonal Antibody can be used in WB. |
Synonyms | GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114 |
Ig Type | IgG |
Reactivity | Human (predicted:Mouse,Rat) |
Verified Activity | Sample: 293T Cell (Human) Lysate at 30 μg Primary: Anti-GCSF Receptor (TMAB-00485) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 95 kDa Observed band size: 120 kDa |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Isoform 2: Secreted (Probable). Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U937 cells. Isoform GSCFR-3 is highly exp |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. |
Immunogen | KLH conjugated synthetic peptide: human G-CSFR |
Antigen Species | Human |
Gene Name | CSF3R |
Gene ID | |
Protein Name | Granulocyte colony-stimulating factor receptor |
Uniprot ID | |
Biology Area | Growth factor receptors,CSFs,Surface Molecules |
Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
Molecular Weight | Theoretical: 95 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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