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IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: TCGF, T-Cell Growth Factor, Interleukin-2, IL-2, IL2, Aldesleukin) Copy Product InfoSynonyms: TCGF, T-Cell Growth Factor, Interleukin-2, IL-2, IL2, Aldesleukin
Catalog No. TMPJ-00036 Copy Product Info
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 16-18 KDa and the accession number is P60568.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $129 | - | In Stock | |
| 10 µg | $213 | 2-4 weeks | 2-4 weeks | |
| 20 µg | $355 | 2-4 weeks | 2-4 weeks | |
| 50 µg | $625 | 2-4 weeks | 2-4 weeks | |
| 100 µg | $963 | 2-4 weeks | 2-4 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 90% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Loaded Human IL-2RA-Fc on Protein A Biosensor, can bind Biotinylated Human IL-2-His-Avi with an affinity constant of 8.60 nM as determined in BLI assay. (Regularly tested)
2. Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.2 ng/ml. (Regularly tested)3. Immobilized Human IL-2RA-His at 2μg/ml (100 μl/well)can bind Human IL-2-His-Avi. The ED50 of Human IL-2-His-Avi is 6.45 ng/ml. (Regularly tested) |
| Description | IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 16-18 KDa and the accession number is P60568. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis-Avi |
| Accession Number | P60568 |
| Amino Acid | Ala21-Thr153 |
| Construction | Ala21-Thr153 |
| Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TCGF, T-Cell Growth Factor, Interleukin-2, IL-2, IL2, Aldesleukin |
| Research Background | Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. |
| Molecular Weight | 16-18 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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