Siglec-15 Protein, Human, Recombinant (hFc)

Name: Siglec-15 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPS-00127
Rating: 4.5 (1 reviews)

(Synonyms: SIGLEC-15, HsT1361, CD33L3) Copy Product Info

Synonyms: SIGLEC-15, HsT1361, CD33L3

Catalog No. TMPS-00127 Copy Product Info

Siglec-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q6ZMC9.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$70	7-10 days	7-10 days
10 µg	$112	7-10 days	7-10 days
20 µg	$183	7-10 days	7-10 days
50 µg	$360	7-10 days	7-10 days
100 µg	$498	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,890	7-10 days	7-10 days
1 mg	$3,390	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Immobilized Anti-Siglec15 at 1.0 μg/ml (100 μl/well) can bind Siglec-15, hFc, Human with a EC 50 = 5.184 ng/ml and a linear range of 0.064−200.0 ng/ml when detected by Mouse Anti–Human IgG Fc-HRP.
Description	Siglec-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q6ZMC9.
Species	Human
Expression System	HEK293 Cells
Tag	hFc
Accession Number	Q6ZMC9
Construction	Phe20-Thr263
Protein Purity	> 90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SIGLEC-15, HsT1361, CD33L3
Research Background	Siglec-15 preferentially recognizes the Neu5Acalpha2-6GalNAcalpha- structure. Siglec-15 associates with the activating adaptor proteins DNAX activation protein (DAP)12 and DAP10 via its lysine residue in the transmembrane domain. Siglec-15 is the second human Siglec identified to have an activating signaling potential; unlike Siglec-14, however, it does not have an inhibitory counterpart.

Chemical Properties

Molecular Weight

~54.3 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.