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Anti-IL-12 p70 Antibody (20C2)
😃Good
Catalog No. T9901A-121
Anti-IL-12 p70 Antibody (20C2) is an anti-human IL-12 p70 monoclonal antibody of the IgG1 isotype, and it acts by suppressing the production of interferon-gamma. Anti-IL-12 p70 Antibody (20C2) is applicable for research studies investigating inflammatory conditions where IL-12 signaling contributes to disease pathogenesis. Anti-IL-12 p70 Antibody (20C2) is recommended to be paired with an appropriate isotype control, specifically Rat IgG1 kappa, Isotype Control.
Anti-IL-12 p70 Antibody (20C2)
Anti-IL-12 p70 Antibody (20C2)
😃Good
Purity: 95%
Catalog No. T9901A-121
Anti-IL-12 p70 Antibody (20C2) is an anti-human IL-12 p70 monoclonal antibody of the IgG1 isotype, and it acts by suppressing the production of interferon-gamma. Anti-IL-12 p70 Antibody (20C2) is applicable for research studies investigating inflammatory conditions where IL-12 signaling contributes to disease pathogenesis. Anti-IL-12 p70 Antibody (20C2) is recommended to be paired with an appropriate isotype control, specifically Rat IgG1 kappa, Isotype Control.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $182 | - | In Stock | |
| 5 mg | $539 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $868 | 2-4 weeks | 2-4 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Target IL-12p70
| Description | Anti-IL-12 p70 Antibody (20C2) is an anti-human IL-12 p70 monoclonal antibody of the IgG1 isotype, and it acts by suppressing the production of interferon-gamma. Anti-IL-12 p70 Antibody (20C2) is applicable for research studies investigating inflammatory conditions where IL-12 signaling contributes to disease pathogenesis. Anti-IL-12 p70 Antibody (20C2) is recommended to be paired with an appropriate isotype control, specifically Rat IgG1 kappa, Isotype Control. |
| In vitro | Anti-IL-12 p70 Antibody (20C2) (20 μg/mL) significantly inhibited the production of IFN-γ in peripheral blood mononuclear cells (PBMCs) derived from Homo sapiens, while Anti-IL-12 p70 Antibody (20C2) (10 μg/mL) markedly promoted the production of IL-12 p70 and IL-12 p40 in PBMCs [1]. Anti-IL-12 p70 Antibody (20C2) (5 μg/mL) effectively suppressed the production of IFN-γ in synovial tissue cells of Homo sapiens [2]. |
| Clone | 20C2 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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