Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].
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Description | Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1]. |
In vitro | Mps1-IN-6 (compound 31) (0-10 µM; 72 h) exhibits antiproliferative activity with IC50 values of 0.221 µM in MDA-MB-468 cells, >10 µM in MCF-7 cells, >10 µM in REB cells, 0.823 µM in MV4-11 cells, and >10 µM in HT-29 cells [1]. |
In vivo | Mps1-IN-6, administered intravenously at doses of 30 and 60 mg/kg daily for 21 days, exhibited antitumor activity in mice [1]. |
Molecular Weight | 633.74 |
Formula | C35H39N9O3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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