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Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His)

Catalog No. TMPY-04032
Synonyms: Kal, mGk-6, Klk1b6, kallikrein 1, Klk6, 0610007D04Rik

KLK1 (Kallikrein 1) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human tissue kallikrein (KLK1) is a serine protease, a component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its anti-inflammatory, antiapoptotic, antifibrotic, and antioxidative actions. Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension. Diseases associated with KLK1 include Kallikrein, Decreased Urinary Activity Of and Hereditary Angioedema.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
Description KLK1 (Kallikrein 1) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human tissue kallikrein (KLK1) is a serine protease, a component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its anti-inflammatory, antiapoptotic, antifibrotic, and antioxidative actions. Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension. Diseases associated with KLK1 include Kallikrein, Decreased Urinary Activity Of and Hereditary Angioedema.
Species Mouse
Expression System HEK293
Tag His
Accession Number P15947
Synonyms Kal, mGk-6, Klk1b6, kallikrein 1, Klk6, 0610007D04Rik
Construction A DNA sequence encoding the mouse KLK1 (P15947) (Met1-Asp261) was expressed with a C-terminal polyhistidine tag.
Protein Purity > 90 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 28.3 kDa
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Lyophilized from sterile 25 mM Tris, 5 mM CaCl2, 0. 15 M NaCl, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background KLK1 (Kallikrein 1) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human tissue kallikrein (KLK1) is a serine protease, a component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its anti-inflammatory, antiapoptotic, antifibrotic, and antioxidative actions. Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension. Diseases associated with KLK1 include Kallikrein, Decreased Urinary Activity Of and Hereditary Angioedema.

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Keywords

Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) Kal mGk-6 Klk1b6 kallikrein 1 Klk6 0610007D04Rik recombinant recombinant-proteins proteins protein

 

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