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Kaempferol 3-O-β-D-galactopyranoside

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Catalog No. TN1823Cas No. 23627-87-4
Alias Kaempferol-3-O-galactoside, Kaempferol 3-O-beta-D-galactoside

Kaempferol 3-O-β-D-galactopyranoside possesses antioxidant, anti-inflammatory, and antinociceptive activities.

Kaempferol 3-O-β-D-galactopyranoside

Kaempferol 3-O-β-D-galactopyranoside

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Purity: 99.22%
Catalog No. TN1823Alias Kaempferol-3-O-galactoside, Kaempferol 3-O-beta-D-galactosideCas No. 23627-87-4
Kaempferol 3-O-β-D-galactopyranoside possesses antioxidant, anti-inflammatory, and antinociceptive activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$128-In Stock
5 mg$289-In Stock
10 mg$455-In Stock
25 mg$733-In Stock
50 mg$987-In Stock
1 mL x 10 mM (in DMSO)$333-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.22%
Appearance:Solid
Color:White to Yellow
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Product Introduction

Kaempferol 3-O-β-D-galactopyranoside AI Summary
Kaempferol 3-O-β-D-galactopyranoside displays a variety of bioactivities, showing potential as an inhibitor and therapeutic agent. It inhibits cow milk xanthine oxidase with 16.1% inhibition at 50 µg/mL, indicating its role in mitigating oxidative stress and purine metabolism disorders. The compound also has notable antiviral activity, particularly against RSV Long and PIV3, with IC50 values of 71.7 µg/mL and 53.8 µg/mL, respectively. However, it shows limited effectiveness against influenza virus type A H1N1 with an IC50 greater than 300.0 µg/mL. Cytotoxicity against MDCK cells is noted with an IC50 of 143.3 µg/mL. Additionally, Kaempferol 3-O-β-D-galactopyranoside exhibits moderate antileishmanial activity against Leishmania peruviana and Leishmania braziliensis promastigotes with IC50 values of 53340.0 nM and 52460.0 nM, respectively, and cytotoxicity to BALB/c mouse J774.2 cells with an IC50 of 161320.0 nM. It inhibits rabbit lung ACE with an IC50 of 260,000.0 nM and demonstrates inhibition of Saccharomyces cerevisiae alcohol dehydrogenase at an IC50 of 70300.0 nM. Moreover, the compound shows antioxidant activity via DPPH radical scavenging, albeit with limited efficacy (4.5% inhibition at 250 µM and an IC50 greater than 100000.0 nM). Lastly, it exhibits hepatoprotective activity in Wistar rat hepatocytes against tert-butyl hydroperoxide-induced oxidative stress, enhancing cell viability to 191.0% at 60 µg/mL. These multifaceted activities highlight Kaempferol 3-O-β-D-galactopyranoside's potential in various therapeutic contexts..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Kaempferol 3-O-β-D-galactopyranoside possesses antioxidant, anti-inflammatory, and antinociceptive activities.
SynonymsKaempferol-3-O-galactoside, Kaempferol 3-O-beta-D-galactoside
Chemical Properties
Molecular Weight448.38
FormulaC21H20O11
Cas No.23627-87-4
SmilesOC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@H]1O
Relative Density.1.79 g/cm3 at 20℃
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (133.82 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.23 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2303 mL11.1513 mL22.3025 mL111.5126 mL
5 mM0.4461 mL2.2303 mL4.4605 mL22.3025 mL
10 mM0.2230 mL1.1151 mL2.2303 mL11.1513 mL
20 mM0.1115 mL0.5576 mL1.1151 mL5.5756 mL
50 mM0.0446 mL0.2230 mL0.4461 mL2.2303 mL
100 mM0.0223 mL0.1115 mL0.2230 mL1.1151 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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