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p32 Inhibitor M36

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Catalog No. T16423Cas No. 802555-85-7
Alias M36

p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.

p32 Inhibitor M36

p32 Inhibitor M36

😃Good
Catalog No. T16423Alias M36Cas No. 802555-85-7
p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$895 days5 days
100 mg$9976-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
In vitro
p32 Inhibitor M36 is selective for p32 overexpressing cells. p32 Inhibitor M36 inhibits SF188 glioma cell proliferation (IC50: 77.9 μM in complete media) and is much more potent under low glucose conditions (IC50: 7.3 μM). p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres (IC50: 2.8 μM)[1].
SynonymsM36
Chemical Properties
Molecular Weight448.52
FormulaC23H28N8O2
Cas No.802555-85-7
SmilesO=C(NCCCNC(=O)Nc1cccc(c1)C1=NCCN1)Nc1cccc(c1)C1=NCCN1
Relative Density.1.39 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5 mg/mL (11.15 mM), Sonication and heating to 80℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2296 mL11.1478 mL22.2955 mL111.4777 mL
5 mM0.4459 mL2.2296 mL4.4591 mL22.2955 mL
10 mM0.2230 mL1.1148 mL2.2296 mL11.1478 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

p-32 Inhibitor M36p32 Inhibitor M36p32M-36M 36
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