store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4).1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer cells when used at a concentration of 50 μM. PRGL493 (5 μM) reduces production of progesterone induced by 8-Br-cyclic AMP (8-Br-cAMP) in MA-10 Leydig tumor cells. It inhibits tumor growth in a PC3 mouse xenograft model when administered at a dose of 0.25 mg/kg.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 59.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 239.00 | |
25 mg | In stock | Inquiry | |
50 mg | In stock | Inquiry |
Description | PRGL493 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4).1It inhibits formation of arachidonoyl-CoA (AA-CoA) from arachidonic acid in, as well as the proliferation and migration of, PC3 and MDA-MB-231 cancer cells when used at a concentration of 50 μM. PRGL493 (5 μM) reduces production of progesterone induced by 8-Br-cyclic AMP (8-Br-cAMP) in MA-10 Leydig tumor cells. It inhibits tumor growth in a PC3 mouse xenograft model when administered at a dose of 0.25 mg/kg. |
Molecular Weight | 451.48 |
Formula | C25H21N7O2 |
CAS No. | 2479378-45-3 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: 1 mg/mL
DMSO: 4.5 mg/mL (10.0 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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PRGL493 2479378-45-3 Others PRGL 493 PRGL-493 inhibitor inhibit