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Anti-XPO1 Antibody (2H608)

(Synonyms: XPO 1, Exportin-1, Exp1, CRM1, Chromosome region maintenance 1 protein homolog) Copy Product Info
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Synonyms: XPO 1, Exportin-1, Exp1, CRM1, Chromosome region maintenance 1 protein homolog

Catalog No. TMAC-00982 Copy Product Info
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Anti-XPO1 Antibody (2H608) is a Rabbit antibody targeting XPO1. Anti-XPO1 Antibody (2H608) can be used in FCM,ICC,IF,IHC,WB.
Anti-XPO1 Antibody
(2H608)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-XPO1 Antibody (2H608) is a Rabbit antibody targeting XPO1. Anti-XPO1 Antibody (2H608) can be used in FCM,ICC,IF,IHC,WB.
SynonymsXPO 1, Exportin-1, Exp1, CRM1, Chromosome region maintenance 1 protein homolog
Ig Type
IgG
Clone
2H608
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500; IHC: 1:50-100; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundProtein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin alpha1 and karyopherin beta1 subunits. p62 glycoprotein is a nucleoporin that is not only involved in the nuclear import of proteins, but also the export of nascent mRNA strands. NTF2 (nuclear transport factor 2) interacts with nucleoporin p62 as a homodimer composed of two monomers, and may be an obligate component of functional p62. CRM1 has been shown to be an export receptor for leucine-rich proteins that contain the nuclear export signal (NES).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: within C terminal human CRM1
Antigen Species
Human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 123 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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